BDBM50079866 (+)-15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,11.04,9]heptadeca-2(11),3,5,7,9,14-hexaen-3-amine::(-)-15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,11.04,9]heptadeca-2(11),3,5,7,9,14-hexaen-3-amine::(rac)15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,11.04,9]heptadeca-2(11),3,5,7,9,14-hexaen-3-amine::15-ethyl-7-methyl-(1R,13S)-10-azoniatetracyclo[11.3.1.02,11.04,9]heptadeca-2,4,6,8,10,14-hexaen-3-amine::15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,11.04,9]heptadeca-2(11),3,5,7,9,14-hexaen-3-amine::CHEMBL322343::rac-huprine H5

SMILES CCC1=CC2CC(C1)c1c(C2)nc2cc(C)ccc2c1N

InChI Key

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50079866   

TargetAcetylcholinesterase(Bovine)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079866((rac)15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,...)
Affinity DataIC50: 12nMAssay Description:Compound was evaluated for the inhibition of acetylcholinesterase of bovine erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079866((rac)15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,...)
Affinity DataIC50: 208nMAssay Description:Inhibition of butyrylcholinesterase (BChE) in human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079866((rac)15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,...)
Affinity DataIC50: 12nMAssay Description:Inhibition of acetylcholinesterase (AChE)activity in bovine erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079866((rac)15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,...)
Affinity DataIC50: 208nMAssay Description:Inhibition of butyrylcholinesterase (BChE) activity in human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079866((rac)15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,...)
Affinity DataIC50: 208nMAssay Description:Inhibition of butyrylcholinesterase (BChE) activity in human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079866((rac)15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,...)
Affinity DataIC50: 12nMAssay Description:Inhibition of acetylcholinesterase (AChE)activity in bovine erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079866((rac)15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,...)
Affinity DataIC50: 115nMAssay Description:Inhibition of butyrylcholinesterase (BChE) activity in human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079866((rac)15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,...)
Affinity DataIC50: 12nMAssay Description:Inhibition of acetylcholinesterase (AChE)activity in bovine erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079866((rac)15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,...)
Affinity DataIC50: 12nMAssay Description:Inhibition of bovine erythrocyte AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50079866((rac)15-ethyl-7-methyl-10-azatetracyclo[11.3.1.02,...)
Affinity DataIC50: 4.5nMAssay Description:In vitro inhibitory activity against bovine acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed