BDBM50079810 2-[1-[5-amino-2-isopropyl-6-sulfanyl-(2S,3E,5R)-3-hexenyl]-4-phenoxy-(2S,4S)-tetrahydro-1H-2-pyrrolylcarboxamido]-4-methylsulfanyl-(2S)-butanoic acid with di( TFA)::CHEMBL67663

SMILES CSCC[C@H](NC(=O)[C@@H]1C[C@@H](CN1C[C@H](\C=C\[C@@H](N)CS)C(C)C)Oc1ccccc1)C(O)=O

InChI Key InChIKey=NWNLGHVZFIYUBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079810   

LigandPNGBDBM50079810(2-[1-[5-amino-2-isopropyl-6-sulfanyl-(2S,3E,5R)-3-...)
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50079810(2-[1-[5-amino-2-isopropyl-6-sulfanyl-(2S,3E,5R)-3-...)
Affinity DataIC50: 17nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed