BDBM50079806 2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(2-propylphenoxy)-(2S,4S)-tetrahydro-1H-2-pyrrolylcarboxamido]-4-methylsulfanyl-(2S)-butanoic acid with di( TFA)::CHEMBL305584

SMILES CCCc1ccccc1O[C@H]1C[C@H](N(C\C=C\[C@@H](N)CS)C1)C(=O)N[C@@H](CCSC)C(O)=O

InChI Key InChIKey=KCVLNHHETHSZOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50079806   

LigandPNGBDBM50079806(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(2-p...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
LigandPNGBDBM50079806(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(2-p...)
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed