BDBM50079791 CHEMBL304823::methyl 2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-butylphenoxy)-(2S,4S)-tetrahydro-1H-2-pyrrolylcarboxamido]-4-methylsulfanyl-(2S)-butanoate with di( TFA)

SMILES CCCCc1ccc(O[C@H]2C[C@H](N(C\C=C\[C@@H](N)CS)C2)C(=O)N[C@@H](CCSC)C(=O)OC)cc1

InChI Key InChIKey=QVGZQJFDCNPOLG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50079791   

LigandPNGBDBM50079791(methyl 2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed