BDBM50079578 CHEMBL3417504

SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)C2CC12

InChI Key InChIKey=FJHKZEVPGYADEG-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50079578   

TargetCytochrome P450 1A2(Human)
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079578(CHEMBL3417504)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079578(CHEMBL3417504)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079578(CHEMBL3417504)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079578(CHEMBL3417504)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079578(CHEMBL3417504)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079578(CHEMBL3417504)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079578(CHEMBL3417504)
Affinity DataKi:  3.70nMAssay Description:Binding affinity to human histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Teva Global R & D.

Curated by ChEMBL
LigandPNGBDBM50079578(CHEMBL3417504)
Affinity DataKi:  13nMAssay Description:Binding affinity to rat histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed