BDBM50079390 4-Benzyl-1-(2-phenoxy-ethyl)-piperidine::CHEMBL102659

SMILES C(CN1CCC(Cc2ccccc2)CC1)Oc1ccccc1

InChI Key InChIKey=HRBKFQYSVXXYDE-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50079390   

LigandPNGBDBM50079390(4-Benzyl-1-(2-phenoxy-ethyl)-piperidine | CHEMBL10...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against NMDA responses at NR1A/2C receptors expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50079390(4-Benzyl-1-(2-phenoxy-ethyl)-piperidine | CHEMBL10...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against NMDA responses at cloned NR1A/2A receptors expressed in Xenopus oocytes More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50079390(4-Benzyl-1-(2-phenoxy-ethyl)-piperidine | CHEMBL10...)
Affinity DataIC50: 630nMAssay Description:In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50079390(4-Benzyl-1-(2-phenoxy-ethyl)-piperidine | CHEMBL10...)
Affinity DataKi:  0.930nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor (unknown origin) assessed as inhibition constant by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50079390(4-Benzyl-1-(2-phenoxy-ethyl)-piperidine | CHEMBL10...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor (unknown origin) assessed as inhibition constant by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed