BDBM50079370 CHEMBL3417001

SMILES COc1cc(N)c(Cl)cc1C(=O)CCC1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=LVVYCYIWSNRYGP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079370   

TargetAcetylcholinesterase(Human)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079370(CHEMBL3417001)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human erythrocyte AChE pre-incubated for 5 mins before acetylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079370(CHEMBL3417001)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of equine serum BuChE pre-incubated for 5 mins before butyrylthiocholine iodide substrate by Ellman' methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cermn

Curated by ChEMBL
LigandPNGBDBM50079370(CHEMBL3417001)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]GR113808 from 5-HT4R in guinea pig brain membranes incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed