BDBM50079331 2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one::2-(2-Chloro-phenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one ( (+/-)Flavopiridol)::CHEMBL418203::Flavopiridol

SMILES CN1CCC([C@@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl

InChI Key InChIKey=BIIVYFLTOXDAOV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50079331   

LigandPNGBDBM50079331(Flavopiridol | CHEMBL418203 | 2-(2-Chloro-phenyl)-...)
Affinity DataIC50: 485nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed
LigandPNGBDBM50079331(Flavopiridol | CHEMBL418203 | 2-(2-Chloro-phenyl)-...)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed
LigandPNGBDBM50079331(Flavopiridol | CHEMBL418203 | 2-(2-Chloro-phenyl)-...)
Affinity DataIC50: 155nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed
LigandPNGBDBM50079331(Flavopiridol | CHEMBL418203 | 2-(2-Chloro-phenyl)-...)
Affinity DataIC50: 663nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed
LigandPNGBDBM50079331(Flavopiridol | CHEMBL418203 | 2-(2-Chloro-phenyl)-...)
Affinity DataIC50: 221nMAssay Description:Inhibition of HCT116 cell proliferation after 72hr of incubation with compounds was determined by SRB Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
UniversitäT Hamburg

Curated by ChEMBL
LigandPNGBDBM50079331(Flavopiridol | CHEMBL418203 | 2-(2-Chloro-phenyl)-...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed