BDBM50079306 3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-carboxylic acid [2-(4-methyl-piperazin-1-yl)-ethyl]-amide::CHEMBL99591

SMILES CC(C)n1c2ccccc2n(C(=O)NCCN2CCN(C)CC2)c1=O

InChI Key InChIKey=QVSGADMNEWLGPY-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079306   

LigandPNGBDBM50079306(3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 3 receptor in rat entorhinal cortex using [3H]-LY 278584 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Faes

Curated by ChEMBL
LigandPNGBDBM50079306(3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...)
Affinity DataKi:  91nMAssay Description:Binding affinity against 5-hydroxytryptamine 4 receptor in guinea pig striatum using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Paris-Sud University

Curated by ChEMBL
LigandPNGBDBM50079306(3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...)
Affinity DataKi:  91.9nMAssay Description:Tested for 5-hydroxytryptamine 4 receptor antagonist activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed