BDBM50079274 (4aR,6R,7R,8aR)-1-(4-Fluoro-benzyl)-7-(4-phenyl-piperidin-1-yl)-decahydro-quinolin-6-ol::CHEMBL95857::trans-trans-1-(4-fluorobenzyl)-7-(4-phenylpiperidin-1-yl)-decahydroquinolin-6-ol

SMILES O[C@@H]1C[C@H]2CCCN(Cc3ccc(F)cc3)[C@@H]2C[C@H]1N1CCC(CC1)c1ccccc1

InChI Key InChIKey=VYMHDKJVVMXTRF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50079274   

TargetVesicular acetylcholine transporter(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079274(trans-trans-1-(4-fluorobenzyl)-7-(4-phenylpiperidi...)
Affinity DataKi:  0.990nMAssay Description:Displacement of [3H]vesamicol from Vesicular Acetylcholine Transporter (VAChT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079274(trans-trans-1-(4-fluorobenzyl)-7-(4-phenylpiperidi...)
Affinity DataKi:  21nMAssay Description:Binding affinity against Sigma opioid receptor type 1 in guinea pig brain membranes using [3H](+)-pentazocine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50079274(trans-trans-1-(4-fluorobenzyl)-7-(4-phenylpiperidi...)
Affinity DataKi:  127nMAssay Description:Binding affinity against Sigma opioid receptor type 2 in rat liver membranes using [3H]DTG (DuPont-NEN) as radioligand in the presence of (+)-pentazo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed