BDBM50078817 1-[4-(10-Methoxy-8-methyl-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone::CHEMBL294476

SMILES COc1cc(C)cc2CCc3cccnc3C(C3CCN(CC3)C(=O)Cc3cc[n+]([O-])cc3)c12

InChI Key InChIKey=AZSSJFMPAFMYJU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50078817   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Schering-Plough Research Institute

Curated by ChEMBL

LigandBDBM50078817(1-[4-(10-Methoxy-8-methyl-6,11-dihydro-5H-benzo[5,...)Copy SMILESCopy InChI

Affinity DataIC50: 140nMAssay Description:In vitro inhibition of human FarnesyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
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