BDBM50078713 CHEMBL416493::{3-[3-(Pyridin-2-ylamino)-propoxy]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-yl}-acetic acid

SMILES OC(=O)CC1Cc2ccc(OCCCNc3ccccn3)cc2Cc2ccccc12

InChI Key InChIKey=HODBWQCCKYDYPY-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078713   

TargetIntegrin alpha-V/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078713({3-[3-(Pyridin-2-ylamino)-propoxy]-10,11-dihydro-5...)
Affinity DataIC50: 65nMAssay Description:Inhibition of HEK 293 cell adhesion to vitronectin by alpha V beta 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078713({3-[3-(Pyridin-2-ylamino)-propoxy]-10,11-dihydro-5...)
Affinity DataKi:  8nMAssay Description:Binding affinity for non-peptide Vitronectin receptor (alpha V beta 3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078713({3-[3-(Pyridin-2-ylamino)-propoxy]-10,11-dihydro-5...)
Affinity DataKi: >3.00E+4nMAssay Description:Binding affinity for alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed