BDBM50078652 CHEMBL301788::N-[5-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-10-carbonyl)-pyridin-2-yl]-2-chloro-4-fluoro-benzamide

SMILES Fc1ccc(C(=O)Nc2ccc(cn2)C(=O)N2Cc3cccn3Cc3ccccc23)c(Cl)c1

InChI Key InChIKey=PINVZEORCGWDCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078652   

TargetVasopressin V2 receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50078652(N-[5-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 1.10nMAssay Description:In vitro inhibition of (P[3H]-AVP binding towards isolated rat kidney medullary Vasopre ssin V2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50078652(N-[5-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of (Phe-3,4,5 [3H]-) AVP binding towards isolated rat hepatic Vasopressin V1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed