BDBM50078545 Acetic acid (3R,3aS,8aS)-3-(4-carbamimidoyl-butyl)-5-(3-diethylcarbamoyl-phenyl)-2-oxo-3,3a,8,8a-tetrahydro-2H-indeno[2,1-b]pyrrol-1-ylmethyl ester::CHEMBL46993

SMILES CCN(CC)C(=O)c1cccc(c1)-c1ccc2C[C@H]3[C@@H]([C@@H](CCCCC(N)=N)C(=O)N3COC(C)=O)c2c1

InChI Key InChIKey=GKIHXHVLEWLVGT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078545   

TargetProthrombin(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078545(Acetic acid (3R,3aS,8aS)-3-(4-carbamimidoyl-butyl)...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078545(Acetic acid (3R,3aS,8aS)-3-(4-carbamimidoyl-butyl)...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of activated Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50078545(Acetic acid (3R,3aS,8aS)-3-(4-carbamimidoyl-butyl)...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed