BDBM50078536 7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxaline-2-carboxylic acid ethyl ester::CHEMBL83919::ethyl 7-chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxaline-2-carboxylate

SMILES CCOC(=O)c1nc2n(n1)c1ccc(Cl)cc1[nH]c2=O

InChI Key InChIKey=DXAANXIRAMZBPL-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50078536   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50078536(7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...)
Affinity DataEC50:  2.21E+4nMAssay Description:Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstarted by the ability to inhibit the binding of the channel-blocking...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50078536(7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...)
Affinity DataKi:  340nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50078536(7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity towards N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes using [3H]glycine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50078536(7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding selectivity towards N-methyl-D-aspartate glutamate receptor 1 was determined by using [3H]- glycine/NMDAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed