BDBM50078528 7-Chloro-5-ethyl-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxaline-2-carboxylic acid::CHEMBL315484

SMILES CCn1c2cc(Cl)ccc2n2nc(nc2c1=O)C(O)=O

InChI Key InChIKey=OLADZCCQHZHLFC-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078528   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50078528(7-Chloro-5-ethyl-4-oxo-4,5-dihydro-[1,2,4]triazolo...)
Affinity DataEC50: >1.00E+5nMAssay Description:Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstarted by the ability to inhibit the binding of the channel-blocking...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50078528(7-Chloro-5-ethyl-4-oxo-4,5-dihydro-[1,2,4]triazolo...)
Affinity DataKi:  8.80E+4nMAssay Description:Binding affinity towards N-methyl-D-aspartate glutamate receptor 1 in rat cortical membranes using [3H]glycine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Universita' Di Firenze

Curated by ChEMBL
LigandPNGBDBM50078528(7-Chloro-5-ethyl-4-oxo-4,5-dihydro-[1,2,4]triazolo...)
Affinity DataKi:  8.89E+4nMAssay Description:Binding selectivity towards N-methyl-D-aspartate glutamate receptor 1 was determined by using [3H]- glycine/NMDAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed