BDBM50078480 4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol::CHEMBL83781

SMILES Oc1ccc(cc1)C#CCCN1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=DQZBYMUDSJTGLY-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50078480   

LigandPNGBDBM50078480(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was tested for antagonistic activity against rat NR1A/2C receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50078480(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against rat NR1A/2A receptor, expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50078480(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Affinity DataIC50: 290nMAssay Description:Binding affinity against Dopamine receptor D2 from rat using [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50078480(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Affinity DataIC50: 170nMAssay Description:Antagonistic activity against rat NR1A/2B receptor expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50078480(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Affinity DataIC50: 100nMAssay Description:Antagonistic activity against NR1A/2B receptor in frog oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50078480(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against NR1A/2A receptors in frog oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50078480(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against NR1A/2C receptor in frog oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50078480(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2C N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50078480(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Affinity DataIC50: 170nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Cocensys

Curated by ChEMBL
LigandPNGBDBM50078480(4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2A N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed