BDBM50078460 2-Amino-7-(4-isopropyl-benzyl)-3,5-dihydro-pyrrolo[3,2-d]pyrimidin-4-one::2-amino-7-(4-isopropylbenzyl)-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one::CHEMBL82551

SMILES CC(C)c1ccc(Cc2c[nH]c3c2nc(N)[nH]c3=O)cc1

InChI Key InChIKey=YNFSXUMIKXWTHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078460   

TargetPurine nucleoside phosphorylase(Bovine)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50078460(2-amino-7-(4-isopropylbenzyl)-3H-pyrrolo[3,2-d]pyr...)
Affinity DataIC50: 96.6nMAssay Description:Inhibitory activity against calf spleen purine nucleoside phosphorylase (PNP) using inosine as substrate at a concentration of 10 uM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Universidade Federal Da Bahia

Curated by ChEMBL
LigandPNGBDBM50078460(2-amino-7-(4-isopropylbenzyl)-3H-pyrrolo[3,2-d]pyr...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human purine nucleoside phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed