BDBM50078432 (S)-3-[(5-Piperidin-4-yl-thieno[2,3-b]thiophene-2-carbonyl)-amino]-2-(pyridine-3-sulfonylamino)-propionic acid::CHEMBL310350

SMILES OC(=O)[C@H](CNC(=O)c1cc2cc(sc2s1)C1CCNCC1)NS(=O)(=O)c1cccnc1

InChI Key InChIKey=UBYQAAFWURXABG-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078432   

TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078432((S)-3-[(5-Piperidin-4-yl-thieno[2,3-b]thiophene-2-...)
Affinity DataKd:  22nMAssay Description:Equilibrium dissociation constant was measured from displacement of L-762,745 from Fibrinogen receptor of human platelets by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50078432((S)-3-[(5-Piperidin-4-yl-thieno[2,3-b]thiophene-2-...)
Affinity DataIC50: 21nMAssay Description:The compound was tested in vivo for the inhibition of aggregation of human gel-filtered platelets(GFP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed