BDBM50078074 2-Amino-6-methyl-5-(pyridin-4-ylsulfanylmethyl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL74139

SMILES Cc1[nH]c2nc(N)[nH]c(=O)c2c1CSc1ccncc1

InChI Key InChIKey=XMNSSOYJBCPOAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50078074   

TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078074(2-Amino-6-methyl-5-(pyridin-4-ylsulfanylmethyl)-3,...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was evaluated for the inhibition at a given concentration against recombinant human Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50078074(2-Amino-6-methyl-5-(pyridin-4-ylsulfanylmethyl)-3,...)
Affinity DataIC50: 2.60E+4nMAssay Description:Compound was evaluated for the inhibition at a given concentration against Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed