BDBM50078017 CHEMBL3417397

SMILES CC1=NN(C(=O)\C1=C\c1ccc(cc1)-c1ccccc1)c1nc(cs1)-c1ccccc1

InChI Key InChIKey=YPLBYQXNSWCZEB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50078017   

TargetApoptosis regulator Bcl-2(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50078017(CHEMBL3417397)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50078017(CHEMBL3417397)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetApoptosis regulator BAX(Human)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50078017(CHEMBL3417397)
Affinity DataKi:  1.29E+4nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed