BDBM50077900 CHEMBL3417053::US9611229, 31

SMILES Fc1cccc(c1)-n1cc(NCCN2CCN(CC2)C2CCCCC2)nn1

InChI Key InChIKey=JOCJKGKYYAFPNY-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077900   

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve

Curated by ChEMBL

LigandBDBM50077900(CHEMBL3417053 | US9611229, 31)Copy SMILESCopy InChI

Affinity DataKi:  56nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/26/2016
Entry Details Article
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TargetSigma non-opioid intracellular receptor 1(Mouse)
Laboratorios Del Dr. Esteve

US Patent

LigandBDBM50077900(CHEMBL3417053 | US9611229, 31)Copy SMILESCopy InChI

Affinity DataKi:  56.4nMAssay Description:Brain membrane preparation and binding assays for the 61-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y. For...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/29/2019
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL