BDBM50077882 CHEMBL3417049::US9611229, 5

SMILES Clc1ccc(cc1Cl)-n1cc(NCCN2CCOCC2)nn1

InChI Key InChIKey=IMNQHPJWYDWAFX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077882   

LigandPNGBDBM50077882(CHEMBL3417049 | US9611229, 5)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Mouse)
Laboratorios Del Dr. Esteve

US Patent
LigandPNGBDBM50077882(CHEMBL3417049 | US9611229, 5)
Affinity DataKi:  45.8nMAssay Description:Brain membrane preparation and binding assays for the 61-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y. For...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

LigandPNGBDBM50077882(CHEMBL3417049 | US9611229, 5)
Affinity DataKi:  46nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed