BDBM50077879 CHEMBL3417044::US9611229, 39

SMILES Clc1ccc(cc1)-n1cc(NCCN2CCCCC2)nn1

InChI Key InChIKey=UBINOAMCLUHYPL-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077879   

LigandPNGBDBM50077879(CHEMBL3417044 | US9611229, 39)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Mouse)
Laboratorios Del Dr. Esteve

US Patent
LigandPNGBDBM50077879(CHEMBL3417044 | US9611229, 39)
Affinity DataKi:  61.5nMAssay Description:Brain membrane preparation and binding assays for the 61-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y. For...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent

LigandPNGBDBM50077879(CHEMBL3417044 | US9611229, 39)
Affinity DataKi:  62nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed