BDBM50077870 CHEMBL3417079::US9611229, 65

SMILES CCN(CCN1CCOCC1)c1cn(nn1)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=NAZNYMOZTIULTD-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077870   

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve

Curated by ChEMBL

LigandBDBM50077870(CHEMBL3417079 | US9611229, 65)Copy SMILESCopy InChI

Affinity DataKi:  216nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/26/2016
Entry Details Article
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TargetSigma non-opioid intracellular receptor 1(Mouse)
Laboratorios Del Dr. Esteve

US Patent

LigandBDBM50077870(CHEMBL3417079 | US9611229, 65)Copy SMILESCopy InChI

Affinity DataKi:  216nMAssay Description:Brain membrane preparation and binding assays for the 61-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y. For...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/29/2019
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL