BDBM50077862 CHEMBL3417071::US9611229, 49

SMILES C[C@H]1CCC[C@@H](C)N1CCNc1cn(Cc2ccc(F)cc2)nn1

InChI Key InChIKey=NRWZPGMUYWHBKY-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077862   

LigandPNGBDBM50077862(CHEMBL3417071 | US9611229, 49)
Affinity DataIC50: 600nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50077862(CHEMBL3417071 | US9611229, 49)
Affinity DataKi:  99nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor transfected in HEK293 cells after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Mouse)
Laboratorios Del Dr. Esteve

US Patent
LigandPNGBDBM50077862(CHEMBL3417071 | US9611229, 49)
Affinity DataKi:  99.4nMAssay Description:Brain membrane preparation and binding assays for the 61-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y. For...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
Go to US Patent