BDBM50077789 (2S,3R,6S)-4-Oxo-3-(3-phenyl-propyl)-1-oxa-5,10-diaza-cyclotetradecane-2,6-dicarboxylic acid 2-hydroxyamide 6-methylamide::CHEMBL34085

SMILES CNC(=O)[C@@H]1CCCNCCCCO[C@@H]([C@@H](CCCc2ccccc2)C(=O)N1)C(=O)NO

InChI Key InChIKey=UEXHODHUQXSZDN-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50077789   

TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077789((2S,3R,6S)-4-Oxo-3-(3-phenyl-propyl)-1-oxa-5,10-di...)
Affinity DataKi:  4nMAssay Description:Inhibition of Matrix metalloprotease-8 (MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077789((2S,3R,6S)-4-Oxo-3-(3-phenyl-propyl)-1-oxa-5,10-di...)
Affinity DataKi:  4nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077789((2S,3R,6S)-4-Oxo-3-(3-phenyl-propyl)-1-oxa-5,10-di...)
Affinity DataKi:  21nMAssay Description:Inhibition of Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077789((2S,3R,6S)-4-Oxo-3-(3-phenyl-propyl)-1-oxa-5,10-di...)
Affinity DataKi:  21nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077789((2S,3R,6S)-4-Oxo-3-(3-phenyl-propyl)-1-oxa-5,10-di...)
Affinity DataKi:  265nMAssay Description:Inhibition of Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077789((2S,3R,6S)-4-Oxo-3-(3-phenyl-propyl)-1-oxa-5,10-di...)
Affinity DataKi:  265nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077789((2S,3R,6S)-4-Oxo-3-(3-phenyl-propyl)-1-oxa-5,10-di...)
Affinity DataKi:  496nMAssay Description:Inhibition of Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077789((2S,3R,6S)-4-Oxo-3-(3-phenyl-propyl)-1-oxa-5,10-di...)
Affinity DataKi:  496nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed