BDBM50077536 (S)-1-(1,2,3,4-Tetrahydro-isoquinolin-3-yl)-methanol::CHEMBL61489

SMILES OC[C@@H]1Cc2ccccc2CN1

InChI Key InChIKey=ZSKDXMLMMQFHGW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50077536   

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50077536((S)-1-(1,2,3,4-Tetrahydro-isoquinolin-3-yl)-methan...)
Affinity DataKi:  7.99E+3nMAssay Description:Inhibitory activity against bovine adrenal phenylethanolamine N-methyl-transferase (PNMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed
LigandPNGBDBM50077536((S)-1-(1,2,3,4-Tetrahydro-isoquinolin-3-yl)-methan...)
Affinity DataKi:  8.48E+3nMAssay Description:Inhibition of [3H]clonidine binding to the rat alpha-2-adrenoceptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50077536((S)-1-(1,2,3,4-Tetrahydro-isoquinolin-3-yl)-methan...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of bovine adrenal Phenylethanolamine N-MethyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50077536((S)-1-(1,2,3,4-Tetrahydro-isoquinolin-3-yl)-methan...)
Affinity DataKi:  1.50E+4nMAssay Description:In vitro inhibition of PNMT (Phenylethanolamine N-Methyltransferase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed