BDBM50077535 (7-Methanesulfonyl-1,2,3,4-tetrahydro-isoquinolin-3-yl)-methanol::CHEMBL43021

SMILES CS(=O)(=O)c1ccc2CC(CO)NCc2c1

InChI Key InChIKey=WOWGEBWXJOUBNT-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50077535   

TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50077535((7-Methanesulfonyl-1,2,3,4-tetrahydro-isoquinolin-...)
Affinity DataKi:  640nMAssay Description:Inhibition of bovine adrenal Phenylethanolamine N-MethyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50077535((7-Methanesulfonyl-1,2,3,4-tetrahydro-isoquinolin-...)
Affinity DataKi:  640nMAssay Description:Inhibition of PNMT (Phenylethanolamine N-Methyltransferase) in vitro More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50077535((7-Methanesulfonyl-1,2,3,4-tetrahydro-isoquinolin-...)
Affinity DataKi:  640nMAssay Description:Affinity for bovine Phenylethanolamine N-MethyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Bovine)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50077535((7-Methanesulfonyl-1,2,3,4-tetrahydro-isoquinolin-...)
Affinity DataKi:  640nMAssay Description:Inhibitory constant against bovine phenylethanolamine N-methyl-transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetPhenylethanolamine N-methyltransferase(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50077535((7-Methanesulfonyl-1,2,3,4-tetrahydro-isoquinolin-...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibitory constant against human phenylethanolamine N-methyl-transferase over-expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed