BDBM50077450 (R)-2-(4-Methoxy-benzenesulfonyl)-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid hydroxyamide::CHEMBL291758

SMILES COc1ccc(cc1)S(=O)(=O)N1Cc2[nH]c3ccccc3c2C[C@@H]1C(=O)NO

InChI Key InChIKey=FKBDRAKAEJZJEQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077450   

TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077450((R)-2-(4-Methoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against human matrix metalloprotease-8 (human neutrophil collagenase, MMP-8)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077450((R)-2-(4-Methoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Hoechst Marion Roussel

Curated by ChEMBL
LigandPNGBDBM50077450((R)-2-(4-Methoxy-benzenesulfonyl)-2,3,4,9-tetrahyd...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human neutrophil collagenase [Matrix Metalloprotease-8, MMP-8]More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2012
Entry Details Article
PubMed