BDBM50077357 14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-6H-chromeno[4',3':4,5]pyrrolo[2,1-a]isoquinolin-6-one-2-sulphonyl sodium::CHEMBL430776

SMILES COc1ccc(cc1O)-c1c2c(n3ccc4cc(OC)c(OC)cc4c13)c(=O)oc1cc(OS([O-])(=O)=O)c(OC)cc21

InChI Key InChIKey=JMOHRMCZYHDLSW-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50077357   

TargetIntegrase(Human immunodeficiency virus type 1)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50077357(14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-...)
Affinity DataIC50: 8.00E+3nMAssay Description:The compound was tested in vitro for inhibition of HIV-1 replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50077357(14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of terminal cleavage activity of HIV1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50077357(14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity against integrase as yield of terminal cleavage productsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50077357(14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of strand transfer activity of HIV1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed