BDBM50077246 CHEMBL49986::N-[4-(3-Bromo-phenylamino)-pyrido[4,3-d]pyrimidin-7-yl]-acrylamide

SMILES Brc1cccc(Nc2ncnc3cc(NC(=O)C=C)ncc23)c1

InChI Key InChIKey=LBTKBOXSMBAAAQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077246   

TargetEpidermal growth factor receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077246(N-[4-(3-Bromo-phenylamino)-pyrido[4,3-d]pyrimidin-...)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of phosphorylation of glutamic acid/tyrosine random copolymer by isolated epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077246(N-[4-(3-Bromo-phenylamino)-pyrido[4,3-d]pyrimidin-...)
Affinity DataIC50: 108nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of epidermal growth factor receptor (EGFR) in A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed