BDBM50077237 CHEMBL53690::N-[4-(3-Trifluoromethyl-phenylamino)-quinazolin-6-yl]-acrylamide

SMILES FC(F)(F)c1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1

InChI Key InChIKey=LSYGGBSRDNYACG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077237   

TargetEpidermal growth factor receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077237(N-[4-(3-Trifluoromethyl-phenylamino)-quinazolin-6-...)
Affinity DataIC50: 0.910nMAssay Description:Inhibition of phosphorylation of glutamic acid/tyrosine random copolymer by isolated epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50077237(N-[4-(3-Trifluoromethyl-phenylamino)-quinazolin-6-...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of EGF-stimulated autophosphorylation of epidermal growth factor receptor in A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed