BDBM50077161 (R)-2-[5-(4-Butoxy-phenylethynyl)-thiophene-2-sulfonylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL49499

SMILES CCCCOc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI Key InChIKey=PBUVCYINXCCIRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077161   

TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50077161((R)-2-[5-(4-Butoxy-phenylethynyl)-thiophene-2-sulf...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Matrix metalloprotease-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50077161((R)-2-[5-(4-Butoxy-phenylethynyl)-thiophene-2-sulf...)
Affinity DataIC50: 3.90nMAssay Description:Inhibitory activity against Matrix metalloprotease-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed