BDBM50077149 (R)-3-Methyl-2-[5-(4-phenoxy-phenylethynyl)-thiophene-2-sulfonylamino]-butyric acid::CHEMBL291213

SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(s1)C#Cc1ccc(Oc2ccccc2)cc1)C(O)=O

InChI Key InChIKey=SDUKSXDVVHERIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50077149   

TargetMatrix metalloproteinase-9(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50077149((R)-3-Methyl-2-[5-(4-phenoxy-phenylethynyl)-thioph...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against Matrix metalloprotease-9 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50077149((R)-3-Methyl-2-[5-(4-phenoxy-phenylethynyl)-thioph...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against Matrix metalloprotease-2 (concentration required for 50% inhibition of enzyme activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed