BDBM50077096 CHEMBL25802::Trans-11-Trifluoromethyl-2,3,4,4a,5,6,8,12b-octahydro-1H-6,8-diaza-benzo[a]anthracen-9-one

SMILES FC(F)(F)c1cc(=O)[nH]c2cc3NC[C@H]4CCCC[C@@H]4c3cc12

InChI Key InChIKey=HMVSJZUUGDCVTI-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077096   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077096(Trans-11-Trifluoromethyl-2,3,4,4a,5,6,8,12b-octahy...)
Affinity DataEC50:  2nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077096(Trans-11-Trifluoromethyl-2,3,4,4a,5,6,8,12b-octahy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells was determined as a function of maximal inhibition of dihydrotestosterone u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077096(Trans-11-Trifluoromethyl-2,3,4,4a,5,6,8,12b-octahy...)
Affinity DataKi:  15nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed