BDBM50077095 CHEMBL281945::Trans-7-Methyl-4-trifluoromethyl-6-(3,3,3-trifluoro-propyl)-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one

SMILES C[C@H]1CNc2cc3[nH]c(=O)cc(c3cc2C1CCC(F)(F)F)C(F)(F)F

InChI Key InChIKey=MXPHFJGIBXHDIU-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50077095   

TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077095(Trans-7-Methyl-4-trifluoromethyl-6-(3,3,3-trifluor...)
Affinity DataIC50: 61nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in CV-1 cells was determined as a function of maximal inhibition of dihydrotestosterone u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077095(Trans-7-Methyl-4-trifluoromethyl-6-(3,3,3-trifluor...)
Affinity DataEC50:  13nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50077095(Trans-7-Methyl-4-trifluoromethyl-6-(3,3,3-trifluor...)
Affinity DataKi:  2nMAssay Description:Binding affinity to the human androgen receptor (hAR), using [3H]DHT as radioligand in a competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed