BDBM50076935 6-(2,3-dihydroxypropylamino)-1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethyltetrahydro-2H-2-pyranyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione::CHEMBL266182

SMILES OCC(O)CNN1C(=O)c2c(C1=O)c1c3cccc(O)c3n(C3OC(CO)C(O)C(O)C3O)c1c1[nH]c3c(O)cccc3c21

InChI Key InChIKey=CGXUCXBMOLKQLI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50076935   

TargetProtein kinase C alpha type(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50076935(6-(2,3-dihydroxypropylamino)-1,11-dihydroxy-12-(3,...)
Affinity DataIC50: 2.00E+5nMAssay Description:In vitro activity evaluated against protein kinase C (using histone II-As as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50076935(6-(2,3-dihydroxypropylamino)-1,11-dihydroxy-12-(3,...)
Affinity DataEC50:  1.00E+3nMAssay Description:In vitro activity against topoisomerase-1 mediated cleavage of supercoiled pBR322 plasmid DNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50076935(6-(2,3-dihydroxypropylamino)-1,11-dihydroxy-12-(3,...)
Affinity DataIC50: 1.80E+5nMAssay Description:In vitro activity against Epidermal growth factor receptor (using poly(Glu4Tyr1) as a substrate)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed