BDBM50076730 (S)-5-(4-Methylamino-phenyl)-2-(4-propyl-benzenesulfonylamino)-pent-4-ynoic acid cyclopentyl-methyl-amide::CHEMBL553108

SMILES CCCc1ccc(cc1)S(=O)(=O)N[C@@H](CC#Cc1ccc(NC)cc1)C(=O)N(C)C1CCCC1

InChI Key InChIKey=VNEQUOUVFXAVMH-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50076730   

TargetProthrombin(Human)
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076730((S)-5-(4-Methylamino-phenyl)-2-(4-propyl-benzenesu...)
Affinity DataKi:  8nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076730((S)-5-(4-Methylamino-phenyl)-2-(4-propyl-benzenesu...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076730((S)-5-(4-Methylamino-phenyl)-2-(4-propyl-benzenesu...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076730((S)-5-(4-Methylamino-phenyl)-2-(4-propyl-benzenesu...)
Affinity DataKi:  1.90E+5nMAssay Description:Inhibitory activity against tissue type plasminogen activator (t-PA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076730((S)-5-(4-Methylamino-phenyl)-2-(4-propyl-benzenesu...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed