BDBM50076722 (S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro-naphthalene-2-sulfonylamino)-pent-4-ynoic acid cyclopentyl-methyl-amide::CHEMBL7587

SMILES CNc1ccc(cc1)C#CC[C@H](NS(=O)(=O)c1ccc2CCCCc2c1)C(=O)N(C)C1CCCC1

InChI Key InChIKey=VYPFJVYVLHXXNE-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50076722   

TargetProthrombin(Human)
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi:  5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi:  5nMAssay Description:In vitro inhibition of human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibitory activity against factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibitory activity against bovine trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Biotech Research Institute

Curated by ChEMBL
LigandPNGBDBM50076722((S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro...)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibitory activity against tissue type plasminogen activator (t-PA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed