BDBM50076648 CHEMBL353553::Morpholine-4-carboxylic acid {3-[5-(4-chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-1-methyl-prop-2-ynyl}-hydroxy-amide

SMILES COc1ccc(cc1)-n1nc(cc1-c1ccc(Cl)cc1)C#CC(C)N(O)C(=O)N1CCOCC1

InChI Key InChIKey=BRTBFGMBOCIGLD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50076648   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50076648(Morpholine-4-carboxylic acid {3-[5-(4-chloro-pheny...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against 5-lipoxygenase (5-LO) in intact rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Rat)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50076648(Morpholine-4-carboxylic acid {3-[5-(4-chloro-pheny...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against cyclooxygenase (COX) in intact rat barophilic leukemia cells (RBL-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed