BDBM50076151 2-((2S,5R)-2-(4-nitrobenzyl)-5-(mercaptomethyl)-3,6-dioxopiperazin-1-yl)-N-tert-butyl-2-phenylacetamide::CHEMBL282581::N-tert-Butyl-2-[(3R,6S)-3-mercaptomethyl-6-(4-nitro-benzyl)-2,5-dioxo-piperazin-1-yl]-2-phenyl-acetamide

SMILES CC(C)(C)NC(=O)C(N1[C@@H](Cc2ccc(cc2)[N+]([O-])=O)C(=O)N[C@@H](CS)C1=O)c1ccccc1

InChI Key InChIKey=UTVKWFNGXGAJBU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50076151   

TargetMatrix metalloproteinase-9(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50076151(N-tert-Butyl-2-[(3R,6S)-3-mercaptomethyl-6-(4-nitr...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50076151(N-tert-Butyl-2-[(3R,6S)-3-mercaptomethyl-6-(4-nitr...)
Affinity DataIC50: 25nMAssay Description:Inhibitory activity against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50076151(N-tert-Butyl-2-[(3R,6S)-3-mercaptomethyl-6-(4-nitr...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Affymax Research Institute

Curated by ChEMBL
LigandPNGBDBM50076151(N-tert-Butyl-2-[(3R,6S)-3-mercaptomethyl-6-(4-nitr...)
Affinity DataIC50: 25nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed