BDBM50076140 (S)-2-{[5-(2-Imidazol-1-yl-ethoxy)-biphenyl-2-carbonyl]-amino}-4-methyl-pentanoic acid methyl ester::CHEMBL27143

SMILES COC(=O)[C@H](CC(C)C)NC(=O)c1ccc(OCCn2ccnc2)cc1-c1ccccc1

InChI Key InChIKey=SOEHLUUYXIKJRU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50076140   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Mouse)
Yale University

Curated by ChEMBL

LigandBDBM50076140((S)-2-{[5-(2-Imidazol-1-yl-ethoxy)-biphenyl-2-carb...)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:In vivo for inhibition of farnesylation based on the inhibition of H-Ras processing.More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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