BDBM50075924 13-Oxo-10,11,12,13-tetrahydro-9H-5,7,9,12-tetraaza-dibenzo[a,de]anthracen-8-carboxylic acid (2-amino-ethyl)-amide::CHEMBL164829

SMILES NCCNC(=O)c1c2NCCN=c2c2c(O)c3ccccc3c3ncnc1c23

InChI Key InChIKey=VXGJDYBLBWXYBM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075924   

TargetCorticotropin-releasing factor receptor 2(Mouse)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075924(13-Oxo-10,11,12,13-tetrahydro-9H-5,7,9,12-tetraaza...)
Affinity DataKi:  650nMAssay Description:Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 2 beta (30% inhibition at 100 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075924(13-Oxo-10,11,12,13-tetrahydro-9H-5,7,9,12-tetraaza...)
Affinity DataKi:  2.05E+3nMAssay Description:Antagonistic activity against [125I]-Tyr-ovine CRF binding to Corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed