BDBM50075849 (S)-2-({2'-Methyl-5-[((E)-2-pyrazin-2-yl)-vinyl]-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid::CHEMBL161476

SMILES CSCC[C@H](NC(=O)c1ccc(\C=C\c2cnccn2)cc1-c1ccccc1C)C(O)=O

InChI Key InChIKey=NNWWMMNANLBUAQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50075849   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50075849((S)-2-({2'-Methyl-5-[((E)-2-pyrazin-2-yl)-vinyl]-b...)Copy SMILESCopy InChI

Affinity DataIC50: 57nMAssay Description:Inhibitory activity against farnesyltransferase (FT) using SPA assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
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