BDBM50075847 (S)-2-{[5-(2-Isoquinolin-4-yl-vinyl)-2'-methyl-biphenyl-2-carbonyl]-amino}-4-methylsulfanyl-butyric acid::CHEMBL164366

SMILES CSCC[C@H](NC(=O)c1ccc(\C=C\c2cncc3ccccc23)cc1-c1ccccc1C)C(O)=O

InChI Key InChIKey=ZGXXVZOEOVXKNI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50075847   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50075847((S)-2-{[5-(2-Isoquinolin-4-yl-vinyl)-2'-methyl-bip...)Copy SMILESCopy InChI

Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against farnesyltransferase (FT) using SPA assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
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