BDBM50075846 (S)-2-{[2'-Methyl-5-(2-pyridin-3-yl-ethyl)-biphenyl-2-carbonyl]-amino}-4-methylsulfanyl-butyric acid::CHEMBL423459

SMILES CSCC[C@H](NC(=O)c1ccc(CCc2cccnc2)cc1-c1ccccc1C)C(O)=O

InChI Key InChIKey=OJMDOBBZTGRJTI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50075846   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50075846((S)-2-{[2'-Methyl-5-(2-pyridin-3-yl-ethyl)-bipheny...)Copy SMILESCopy InChI

Affinity DataIC50: 2.10nMAssay Description:Inhibitory activity against farnesyltransferase (FT) using SPA assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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