BDBM50075823 CHEMBL159435::N-[1-(1-Amino-isoquinolin-6-ylmethyl)-2-oxo-2-piperidin-1-yl-ethyl]-2-(naphthalene-2-sulfonylamino)-acetamide

SMILES Nc1nccc2cc(CC(NC(=O)CNS(=O)(=O)c3ccc4ccccc4c3)C(=O)N3CCCCC3)ccc12

InChI Key InChIKey=JNGWPAXVXOJMED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50075823   

TargetSerine protease 1(Human)
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075823(N-[1-(1-Amino-isoquinolin-6-ylmethyl)-2-oxo-2-pipe...)
Affinity DataIC50: 2.55E+5nMAssay Description:Compound was tested for inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Nv Organon

Curated by ChEMBL
LigandPNGBDBM50075823(N-[1-(1-Amino-isoquinolin-6-ylmethyl)-2-oxo-2-pipe...)
Affinity DataIC50: 5.50E+4nMAssay Description:Compound was tested for inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed