BDBM50075765 4-[3-(2-Bromo-phenyl)-5-(4-chloro-phenyl)-1H-pyrrol-2-yl]-pyridine::CHEMBL436022

SMILES Clc1ccc(cc1)-c1cc(c([nH]1)-c1ccncc1)-c1ccccc1Br

InChI Key InChIKey=OLORAIPIPRFIOH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50075765   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075765(4-[3-(2-Bromo-phenyl)-5-(4-chloro-phenyl)-1H-pyrro...)
Affinity DataIC50: 26nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]glucagon to the human glucagon receptor (GGR) expressed on CHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075765(4-[3-(2-Bromo-phenyl)-5-(4-chloro-phenyl)-1H-pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against p38-alpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075765(4-[3-(2-Bromo-phenyl)-5-(4-chloro-phenyl)-1H-pyrro...)
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity towards glucagon receptor determined by reduction in binding of [125I]glucagon to the human glucagon receptor (GGR) expressed on CHO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075765(4-[3-(2-Bromo-phenyl)-5-(4-chloro-phenyl)-1H-pyrro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human glucagon receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article