BDBM50075674 2-[(E)-2-(4-Fluoro-phenyl)-vinyl]-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone::CHEMBL23556

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C=Cc2ccc(F)cc2)C(=O)CC1

InChI Key InChIKey=WLPAWGDABFYIPX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50075674   

TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075674(2-[(E)-2-(4-Fluoro-phenyl)-vinyl]-3-(4-methanesulf...)
Affinity DataIC50: 2.70E+4nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 1 (hCOX-1) in the human whole blood assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075674(2-[(E)-2-(4-Fluoro-phenyl)-vinyl]-3-(4-methanesulf...)
Affinity DataIC50: 500nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in the human whole blood assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50075674(2-[(E)-2-(4-Fluoro-phenyl)-vinyl]-3-(4-methanesulf...)
Affinity DataIC50: 175nMAssay Description:In vitro potency against human Prostaglandin G/H synthase 2 in transfected CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed